|
KMID : 0376219990350010069
|
|
Chonnam Medical Journal
1999 Volume.35 No. 1 p.69 ~ p.78
|
|
|
Clinical and Bacteriological Studies of Urinary Tract Infection in Children
|
|
Cho Tae-Hyung
Kim Byung-Ju
Ma Jae-Sook
|
|
|
Abstract
|
|
|
|
This study was undertakened to review the clinical features and the antimicrobial susceptibility of cultured organisms in 78 children with symptomatic urinary tract infection (UTI) who were admitted to the Department of Pediatrics, Chonnam University Hospital from January 1994 to December 1998. Among them, causative microorganisms were cultured in 49 patients. Renal sonogram and renal scan using DMSA (dimercaptosuccinic acid) were performed in 78 patients. We reviewed retrospectively the medical records of the patients. Male to female ratio was 1.8 : 1 and UTI was more prevalent in infant. High fever was most frequently observed and other nonspecific systemic manifestations such as poor feeding and vomiting were noted also. Urinalysis at admission revealed pyuria in 68 cases (87%) and hematuria in 34 cases (43%). Pyuria was not observed in 10 patients (20%) with UTI who causative organisms were cultured. UTIs are caused by E. coli (63%), followed by Staphylococcus aureus (6%), Klebsiella species (5%), and Enterococcus (5%). In the vitro antimicrobial susceptibility test, E. coli was relatively sensitive to cefotaxime, amikacin, ciprofloxacin, imipenem, ceftazidime, and sulperazone, but resistant to gentamicin, tetracycline, piperacillin, cephalothin, and especially ampicillin and bactrim. Abnormal echogenicity on renal sonography were noted in 28 cases and cortical defect on DMSA renal scan in 17 cases. Twelve cases had cortical defect on DMSA renal scan without abnormal echogenicity on renal sonogram. Sixteen cases had abnormal echogenicity on renal sonogram without cortical defect on DMSA renal scan. These results indicate that treatment with cefotaxime with an aminoglycoside such as amikacin is preferable in acute febrile UTI. Further studies need to be performed to evaluate the efficacy of bactrim for long-term antibacterial prophylaxis in children with UTI.
|
|
|
KEYWORD
|
|
|
Urinary tract infection, Children.E.coli
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|